| 21 December 2025 | |||
| 21:00 |  Morocco |
 Comoros |
1.304.2011.00 |
| 22 December 2025 | |||
| 16:00 |  Mali |
 Zambia |
1.853.404.40 |
| 19:00 |  South Africa |
 Angola |
2.103.203.30 |
| 22:00 |  Egypt |
 Zimbabwe |
1.553.806.20 |
| 23 December 2025 | |||
| 14:30 |  DR Congo |
 Benin |
2.053.203.60 |
| 17:00 |  Senegal |
 Botswana |
1.404.108.50 |
| 19:30 |  Nigeria |
 Tanzania |
1.603.705.40 |
| 22:00 |  Tunisia |
 Uganda |
1.753.404.90 |
| 24 December 2025 | |||
| 14:30 |  Burkina Faso |
 Equatorial Guinea |
1.903.304.20 |
| 17:00 |  Algeria |
 Sudan |
1.453.907.50 |
| 19:30 |  Côte d’Ivoire |
 Mozambique |
1.603.705.40 |
| 22:00 |  Cameroon |
 Gabon |
1.853.304.40 |
| 26 December 2025 | |||
| 14:30 | Angola |
Zimbabwe |
2.403.002.85 |
| 17:00 | Egypt |
South Africa |
1.803.304.60 |
| 19:30 | Zambia |
Comoros |
1.953.404.10 |
| 22:00 | Morocco |
Mali |
2.103.103.40 |
| 27 December 2025 | |||
| 14:30 | Benin |
Senegal |
5.503.801.55 |
| 17:00 | Botswana |
Nigeria |
6.804.101.45 |
| 19:30 | Tanzania |
Tunisia |
4.903.401.75 |
| 22:00 | Uganda |
DR Congo |
3.603.102.05 |
| 28 December 2025 | |||
| 14:30 | Equatorial Guinea |
Algeria |
5.203.701.60 |
| 17:00 | Sudan |
Burkina Faso |
4.403.201.90 |
| 19:30 | Mozambique |
Cameroon |
4.803.401.80 |
| 22:00 | Gabon |
Côte d’Ivoire |
3.903.301.85 |
| 29 December 2025 | |||
| 16:00 | Zimbabwe |
South Africa |
3.803.101.95 |
| 19:00 | Angola |
Egypt |
4.203.301.75 |
| 30 December 2025 | |||
| 16:00 | Comoros |
Mali |
4.903.401.80 |
| 19:00 | Zambia |
Morocco |
3.603.202.05 |
| 31 December 2025 | |||
| 20:00 | End of AFCON 2025 Group Stage – Knockout Fixtures Confirmed After Midnight | ||